Study of dynamic change of cerebral edema in patients with acute cerebral stroke and role of relieving brain edema by drain and aspiration of hematom with micro-damage puncture

Objective To explore the dynamic change of cerebral edema in acute cerebral stroke patients, and the role of relieving brain edema by drain and aspiration of hematom with micro-damage puncture. Methods 43 cases with acute cerebral stroke (all admission within 24 hours after onset) were divided into three groups: 15 patients accepted the medicine conservative therapy, 16 patients accepted the drain and aspiration of hematom, 12 patients with cerebral infarction. The changes of comprehensive disturbance coefficient in all cases were detected by non-invasive dynamic brain edema monitor at 1st, 3rd, 5th and 7th day.Results The comprehensive disturbance coefficient in focus side was lower than uninjured side both in conservative therapy group and micro-damage puncture treatment group at 1st day. In conservative therapy group, the coefficient in focus side increased (higher than the unaffected side) and reached its peak at 3rd day, and maintained increasing at 7th day. However, in micro-damage puncture group, the coefficient in the focus side was higher than the unaffected side at 3rd day, and then became approximately equal to the unaffected side at 5th day and nearly down to normal at 7th day. It showed significant differences at 3rd, 5th and 7th day between two groups ( P0.01). In infarction group, the comprehensive disturbance coefficient in the focus side was higher than the unaffected 1st day, reached the peak at 5th day and continued for more than 7 days.Conclusions The comprehensive disturbance coefficient takes on dynamical changes in acute cerebral stroke and reflects the course of edema formation. Micro-damage puncture may clear away hematoma effectively and significantly reduce the formation of cerebral edema after intracerebral hemorrhage.