ScholarLens Back to search
2013•Chinese Journal of Health Laboratory TechnologyRequires access

The value of TNF-α,IL-10 for sepsis treatment monitoring in children

Wang Wenjuan

Open publisher page 0 citations

Abstract

Objective:To investigate the value of peripheral tumor necrosis factor-α(TNF-α)and interleukin-10(IL-10)in diagnosis and treatment monitoring in children.Methods: In accordance with Diagnosis and treatment scheme for neonatal sepsis made in 2003,fifty-seven children with were selected to detect the serum level of TNF-α and IL-10 by double-antibody sandwich-ELISA.Results: With disease progress and death,IL-10 level obviously increased(P0.01).IL-10 level and IL-10/TNF-α were significantly higher in severe cases than healed and curative cases(P0.01).Conclusion: IL-10 level and IL-10/TNF-α had certain clinical value in treatment monitoring and prognosis judgement of in children.

About this research paper

What this paper is about

Objective:To investigate the value of peripheral tumor necrosis factor-α(TNF-α)and interleukin-10(IL-10)in diagnosis and treatment monitoring in children.Methods: In accordance with Diagnosis and treatment scheme for neonatal sepsis made in 2003,fifty-seven children with were selected to detect the serum level of TNF-α and IL-10 by double-antibody sandwich-ELISA.Results: With disease progress and death,IL-10 level obviously increased(P0.01).IL-10 level and IL-10/TNF-α were significantly higher in severe cases than healed and curative cases(P0.01).Conclusion: IL-10 level and IL-10/TNF-α had certain clinical value in treatment monitoring and prognosis judgement of in children.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To investigate the value of peripheral tumor necrosis factor-α(TNF-α)and interleukin-10(IL-10)in diagnosis and treatment monitoring in children.Methods: In accordance with Diagnosis and treatment scheme for neonatal sepsis made in 2003,fifty-seven children with were selected to detect the serum level of TNF-α and IL-10 by double-antibody sandwich-ELISA.Results: With disease progress and death,IL-10 level obviously increased(P0.01).IL-10 level and IL-10/TNF-α were significantly higher in severe cases than healed and curative cases(P0.01).Conclusion: IL-10 level and IL-10/TNF-α had certain clinical value in treatment monitoring and prognosis judgement of in children.

Key concepts: Medicine, Tumor necrosis factor alpha, Sepsis, Gastroenterology, Internal medicine, Disease, Interleukin 10, Tumor necrosis factor α

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The value of TNF-α,IL-10 for sepsis treatment monitoring in children — Research Paper | ScholarLens