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Progress in study on therapeutic effect of recombinant human GH for children with idiopathic short stature

Liu Xu-nian

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Abstract

Recombinant human growth hormone(GH) therapy has a certain therapeutic effect for children with idiopathic short stature (ISS), but its effect on final height (FH) is still uncertain. This article reviewed progress in study on effects of growth hormone therapy on bone metabolism,circadian osteocalcin rhythms of prepubertal children with idiopathic short stature, metabolic consequences of growth hormone and psychological effect on boys with short stature.

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What this paper is about

Recombinant human growth hormone(GH) therapy has a certain therapeutic effect for children with idiopathic short stature (ISS), but its effect on final height (FH) is still uncertain. This article reviewed progress in study on effects of growth hormone therapy on bone metabolism,circadian osteocalcin rhythms of prepubertal children with idiopathic short stature, metabolic consequences of growth hormone and psychological effect on boys with short stature.

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Available abstract

Recombinant human growth hormone(GH) therapy has a certain therapeutic effect for children with idiopathic short stature (ISS), but its effect on final height (FH) is still uncertain. This article reviewed progress in study on effects of growth hormone therapy on bone metabolism,circadian osteocalcin rhythms of prepubertal children with idiopathic short stature, metabolic consequences of growth hormone and psychological effect on boys with short stature.

Key concepts: Idiopathic short stature, Short stature, Medicine, Human growth hormone, Growth hormone, Endocrinology, Internal medicine, Circadian rhythm

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