Clinical research of allergen skin prick test in Conghua children with asthma
Chen Wei-ron
Abstract
Chen Wei-ron
Abstract
【Objective】 To learn from the pathogenesis of bronchial asthma in urbanized areas of major allergens and their characteristics,and to guide the selection of specific immunotherapy target.【Method】 382 cases of bronchial asthma in children in remission were given skin prick test,with Germany's Merck Group A Luoge ingestion and inhalation group reagents,histamine solution as a positive control,normal saline as a negative control.【Results】 Asthma,skin prick test positive children was 88.5%.Inhaled allergens positive rate of 81.2%,inhaled allergens to dust mites and house dust mite-positive rate in the high,respectively 77.2% and 71.2%;ingestion of allergens positive rate of 32.7%,ranking the first two 19.9% for shrimp,peanuts,6.3%.Inhaled allergens in the older and younger age group,difference was statistically significant(P0.05),ingestion of allergens in the older and younger age group,difference was not statistically significant(P0.05).Asthma or asthma and allergic rhinitis in children were the most common mites between the two groups differences between mites,mold,animal fur class,cockroaches and weeds allergens positive rate were not statistically significant.【Conclusions】 Conghua region pathogenesis of bronchial asthma inhaled allergens are mainly dust mites,house dust mites,food allergens are mainly into the shrimp,peanuts.Children aged 3 to 14 increased with age in children with asthma,inhaled allergens are more sensitive of common allergens are asthma patients with asthma and rhinitis mainly mites,Followed by mold type,animal fur class,asthma guide provides for the prevention and treatment.
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【Objective】 To learn from the pathogenesis of bronchial asthma in urbanized areas of major allergens and their characteristics,and to guide the selection of specific immunotherapy target.【Method】 382 cases of bronchial asthma in children in remission were given skin prick test,with Germany's Merck Group A Luoge ingestion and inhalation group reagents,histamine solution as a positive control,normal saline as a negative control.【Results】 Asthma,skin prick test positive children was 88.5%.Inhaled allergens positive rate of 81.2%,inhaled allergens to dust mites and house dust mite-positive rate in the high,respectively 77.2% and 71.2%;ingestion of allergens positive rate of 32.7%,ranking the first two 19.9% for shrimp,peanuts,6.3%.Inhaled allergens in the older and younger age group,difference was statistically significant(P0.05),ingestion of allergens in the older and younger age group,difference was not statistically significant(P0.05).Asthma or asthma and allergic rhinitis in children were the most common mites between the two groups differences between mites,mold,animal fur class,cockroaches and weeds allergens positive rate were not statistically significant.【Conclusions】 Conghua region pathogenesis of bronchial asthma inhaled allergens are mainly dust mites,house dust mites,food allergens are mainly into the shrimp,peanuts.Children aged 3 to 14 increased with age in children with asthma,inhaled allergens are more sensitive of common allergens are asthma patients with asthma and rhinitis mainly mites,Followed by mold type,animal fur class,asthma guide provides for the prevention and treatment.
Key concepts: Asthma, Medicine, Mite, Inhalation, Allergen, Immunology, Allergy, Ragweed