Relationship between carotid atherosclerosis and plasma lipids and glucose in patients with type 2 diabetes

Objective To study the relationship between carotid atherosclerosis and plasma lipids and glucose in patients with type 2 diabetes. Methods A total of 100 patients with type 2 diabetes and 40 healthy controls were enrolled.Carotid artery intima-media thickness(IMT) was detected by Ultrasonography and blood HbA1c,plasma lipids(TC,TG,LDL-C,HDL-C) were measured for all subjects. Results The incidence of carotid atherosclerosis in type 2 diabetes patients was significantly higher than in healthy controls(75% vs.25%,P0.01).The mean IMT of Type 2 diabetes patients with carotid artery plaque was significantly greater than those without [(1.42±0.21)mm vs.(1.00±0.18)mm,P0.01].Type 2 diabetes patients with carotid atherosclerosis plaque had higher blood HbA1c and LDL-C,and lower HDL-C(all P0.05) than those without plaque and healthy controls(all P0.05). Conclusions The extent of carotid atherosclerosis is positively correlated with blood glucose and lipids in patients with type 2 diabetes.