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2006•Journal of Inner Mongolia University for the NationalitiesRequires access

The Implementation and Discussion of Algorithm from SNP to Tag SNP

Zhili Pei, Yanchun Liang, Yinan Lu

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Abstract

Because genetyping all the SNP sites cost too much,a spot of tag SNP can provide map information which is approximately the same as more than 15 million SNP sites.Therefore,how to select tag SNP seems to bevery important.This article mainly carries out the algorithm finding tag SNP from SNP based on Linkage Disequilibrium(LD).

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What this paper is about

Because genetyping all the SNP sites cost too much,a spot of tag SNP can provide map information which is approximately the same as more than 15 million SNP sites.Therefore,how to select tag SNP seems to bevery important.This article mainly carries out the algorithm finding tag SNP from SNP based on Linkage Disequilibrium(LD).

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Available abstract

Because genetyping all the SNP sites cost too much,a spot of tag SNP can provide map information which is approximately the same as more than 15 million SNP sites.Therefore,how to select tag SNP seems to bevery important.This article mainly carries out the algorithm finding tag SNP from SNP based on Linkage Disequilibrium(LD).

Key concepts: SNP, Tag SNP, Linkage disequilibrium, SNP genotyping, Molecular Inversion Probe, Computational biology, Linkage (software), SNP array

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