Clinical study of different treatment strategy for AMI patients treated by primary PCI with multi-vessel coronary artery disease

Objective To observe the clinical outcome of patients with acute myocardial infartion(AMI) and multivessel coronary disease(MVD) undergoing primary percuteneous coronary intervention(PCI),whether staged PCI or drug therapy.Evaluate optimal treatment strategy of non-culprit vessels.Methods Data of 151 patients with STEMI and MVD treated by primary PCI were analyzed.Patients were divided into 2 groups,Group 1(n=64)with staged PCI of non-culprit vessels after primary PCI 7-14days,Group 2(n=87)with drug therpy.Comparing clinical and coronary angiographic data,in-hospital and long-term major adverse cardiovascular events(MACE).Results Clinical and angiographic data are similar between two groups.In Group 1 more hospital stay(16.98±5.84 days) than Group 2(11.29±5.00)(P=0.000).Group 1 patients underwent staged PCI 7.9±6.0 days after primary PCI.The mean length of follow-up was 14 months(433.3±325.9days).The incidence of in-hospital MACE was 4.69%in Group 1 and 4.60% in Group 2(P=1.0);the incidence of follow-up MACE was3.13% in Group 1 and 13.79% in Group 2(P=0.026).Conclusions Our data show that staged PCI in STEMI patients with MVD underwent primary PCI is associated with a low incidence of MACE at follow-up.