2015•Unpublished venueRequires access
Analgesic and anti fatigue effects of the extract from Paeoniae Radix Alba
Qin Ya-don
Open publisher page 1 citations
Abstract
Objective To compare analgesic and anti fatigue effects of the ethanol extract and water extract from Paeoniae Radix Alba. Methods The analgesic effects were studied by body twisting caused by acetic acid in mice,and the anti fatigue effects were evaluated through swimming test and lactic acid level in serum. Results Compared with the normal group,the ethanol extract and water extract could significantly reduce the writhing times of the mice,the effect of ethanol extract was stronger than that of water extract,the effects compared with aspirin control group were significantly( P 0. 05); Water extract could significantly prolong the swimming time of mice,meanwhile,both kinds of extracts could significantly decrease lactic acid level in serum in mice after strenuous exercise,and the effect of ethanol extract was stronger than that of water extract。( P 0. 05). Conclusion The ethanol extract and water extract had analgesic effects and the effect of ethanol extract was stronger,but there are less than aspirin control group,meanwhile,the water extract had anti fatigue effects.