Risk Factors of Coronary Heart Disease in Correlation with Restenosis after Transluminal Coronary Angioplasty and Stenting

Objective The purpose of this study is to determinate whether risk factors such as cigarette smoking, diabetes mellitus, hypertension, hypercholesterolaemia, and family history of coronary artery disease (CAD) are correlated with restenosis after coronary angioplasty. Methods Quantitative coronary analysis was made and angiographic characteristics of the lesions were determined in 84 patients with the angiographies of pre-intervention, post-intervention among 440 patients who had undertaken coronary angioplasty or coronary stenting. Angiographic restenosis was defined as at least 50% diameter stenosis on the follow-up angiogram after the initial successful procedure. A multivariable Cox regression was performed to assess factors correlated with restenosis. Results The rate of restenosis of all patients was 40.00% during 6 months. The patients with coronary restenosis had more than one risk factor of CAD. Restenosis was correlated positively with pre-procedure smoking and other risk factors, multivessel disease, lesion types and LDA involvement negatively with stent implantation. Conclusion Restenosis after angioplasty might correlate significantly with pre-procedure smoking, and other risk factors of CAD.