Whole organ perfusion of the cervix using dynamic volume CT in patients with cervical cancer acquisition technique post processing and initial results

Objective To evaluate the application value of whole-organ CT perfusion in the assessment of cervical cancer using the 640-slice CT,and the CT perfusion manifestation of normal tissue and cervical cancer.Methods Twelve histologically proven cervical cancer patients underwent CT perfusion study using a 640-slice CT unit.Abdominal aortic CT value was monitored and automatically triggersed whole-organ CT perfusion scan following contrast-material injection(7 ml/s,350 mg iodine/ml).After image registration,perfusion was determined with the gradient relationship technique and volume regions-of-interest were defined for perfusion measurements.Contrast time-density curves and perfusion maps were generated.Statistical analysis was performed using the t test for analysis perfusion value of the normal tissue and the cervical cancer.Results In all 12 patients,the entire uterus was imaged,and registration could be completed in all cases.The time-density curve ascended quickly.The cervical cancer could be visualized on color maps,and was significantly higher than the surrounding normal tissue.The AF of cervix cancer(255.42±28.14) ml/min/100ml was significantly higher than that of normal tissue(168.34±7.49) ml/min/100ml(t=3.189,P0.05),and could be visualized on colored perfusion maps.Conclusion The 640-slice CT cervical cancer dynamic volume CT perfusion has good maneuver ability and feasibility.As a comprehensive imaging technique in the evaluation of cervical cancer,CT perfusion can evaluate the hemodynamic changes of cervical cancer and is a useful complement to conventional CT scan.