Simultaneous Determination of Residual Contents of 12 Glycol Ethers in Leather and Its Products by Gas Chromatography-Mass Spectrometry Coupled with Microwave-assisted Extraction

An effective method was established for the simultaneous determination of the residual contents of 12 glycol ethers in leather and its products. Glycol ethers in leather and leather products were microwave-assisted extracted at 85 ℃,using methanol as extraction solvent. The extracts were purified with solid phase extraction( SPE) column,and analyzed by gas chromatography-mass spectrometry / selected ions monitoring technique( GC-MS / SIM) with the external standard method. The spiked average recoveries varied from 81. 1% to 95. 9% with relative standard deviations( RSDs) of1. 4%-9. 6%. The limits of quantitation( LOQ,S / N = 10) for analytes were in the range of 0. 05-0. 20 mg / kg. The proposed method was simple,rapid,sensitive and accurate,and could satisfy completely the technical demands for the determination of glycol ethers residual in leather and its products and provide a reference for the relevant testing standard.