2003Chinese Journal of Gastroenterology and HepatologyRequires access

Different expression and analysis of SLP-76 gene in cancer of the digestive tract and adjacent normal mucosa

Liqun Zhao

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Abstract

Objective Confirm the microarray hybridization results and examine the expression of SLP-76 gene in digestive tract cancers and adjacent normal mucosa.MethodsAccording to analysis results of microarray, distinctly differential ly expressed SLP-76 gene was screening out. RT-PCR was applied to check the expression o f SLP-76 in digestive tract cancers and adjacent normal mucosa. ResultsBy RT-PCR examination ,we found that SLP-76 gene over expression in cancer of the digestive tract. ConclusionsDifferent expression of SLP-76 gene in cancer of the digestive tract is found, SLP-76 gene have closely relation with grown in the cancer of digestive tract.It is apossibly potential oncology gene in the cancer of digestive tract. This differential expressio n appeared no tissue specificity with statistical analysis (P=0.9684).

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What this paper is about

Objective Confirm the microarray hybridization results and examine the expression of SLP-76 gene in digestive tract cancers and adjacent normal mucosa.MethodsAccording to analysis results of microarray, distinctly differential ly expressed SLP-76 gene was screening out. RT-PCR was applied to check the expression o f SLP-76 in digestive tract cancers and adjacent normal mucosa. ResultsBy RT-PCR examination ,we found that SLP-76 gene over expression in cancer of the digestive tract. ConclusionsDifferent expression of SLP-76 gene in cancer of the digestive tract is found, SLP-76 gene have closely relation with grown in the cancer of digestive tract.It is apossibly potential oncology gene in the cancer of digestive tract. This differential expressio n appeared no tissue specificity with statistical analysis (P=0.9684).

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Available abstract

Objective Confirm the microarray hybridization results and examine the expression of SLP-76 gene in digestive tract cancers and adjacent normal mucosa.MethodsAccording to analysis results of microarray, distinctly differential ly expressed SLP-76 gene was screening out. RT-PCR was applied to check the expression o f SLP-76 in digestive tract cancers and adjacent normal mucosa. ResultsBy RT-PCR examination ,we found that SLP-76 gene over expression in cancer of the digestive tract. ConclusionsDifferent expression of SLP-76 gene in cancer of the digestive tract is found, SLP-76 gene have closely relation with grown in the cancer of digestive tract.It is apossibly potential oncology gene in the cancer of digestive tract. This differential expressio n appeared no tissue specificity with statistical analysis (P=0.9684).

Key concepts: Digestive tract, Biology, Gene expression, Gene, Microarray analysis techniques, Microarray, Cancer, Gastrointestinal tract

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