Correlation study about quality of life with excessive daytime sleepiness and depression in patients with obstructive sleep apnea hypopnea syndrome

Objective To explore the correlation about the health-related quality of life(HRQoL) with excessive daytime sleepiness(EDS) and depression in patients with obstructive sleep apnea hypopnea syndrome(OSAHS) via different professional scale. Methods Overall 71 people were enrolled in the study(41 patients with OSAHS as case group and 30 normal people as control group).They were measured for HRQoL by using the Medical Outcomes Study Short-Form 36 survey(SF-36),for EDS by using the Epworth Sleepiness Scale(ESS),and for depression by using the Zung self-rating depression scale(SDS). Results The ESS score in OSAHS group was significantly higher than that of control group,(14.68±6.25) scores vs(5.96±2.38) scores(P0.01).The SF-36 scores in OSAHS group were lower than those of control group in four domains to different extent.The most obvious was in the SF domain,VT(59.15±22.82) scores vs(80.33±11.66) scores(P0.01);SF(80.85±14.66) scores vs(90.86±6.67) scores(P0.01);RE(76.59±15.67) scores vs(92.50±6.12) scores(P0.01).The ESS score in OSAHS group was significantly negatively correlated with the SF-36 scores in 3 domains(PF:r=-0.407,P0.01;RP:r=-0.523,P0.01;VT:r=-0.417,P0.01).The SDS score was negatively correlated with the SF-36 score in one domain(SF:r=-0.381,P0.05). Conclusion The HRQoL of OSAHS patients was lower compared with that of normal control people.The poorer HRQoL of patients with OSAHS was strongly correlated with the SDS and ESS score.