Effect of remifentanil combined with propofol anesthetic induction on intubating conditions and hemodynamics

Objective To compare and assess the intubating conditions and hemodynamic changes after anesthetic induction using remifentanil or fentanyl combined with propofol. Methods sixty patients were divided into 2 groups. After anesthetic induction 2 minutes, tracheal intubation was performed. The mean arterial pressure (MAP) and heart rate (HR) were determined before anesthetic induction, 1 minute and 2 minutes after intubation respectively. Tracheal intubating conditions were scored by operator. Results Successful rate of intubation was 100% in both groups. Satisfactory rate of intubating conditions were 80% and 73% in remifentanil group and fentanyl group respectively. The MAP and HR were lower than that baseline after induction(P0.05). After intubation, there was significant differene in MAP between the 2 groups (P0.05). Conclusion The intubating conditions were similar after anesthetic induction using remifentanil or fentanyl combined with propofol. Furthermore, the inhibition of cardiovascular responses to tracheal intubation with remifentanil is more effective than that with fentanyl.