Antitumor activities in vitro of total-lignan from Stellera chamaejasme L.in vitro

The antitumor activities in vitro of total-lignan from Stellera chamaejasme were studied in this paper and the in vitro antitumor activities were determined by a MTT assay and clone formation against human cancer cell lines,such as stomach cancer SGC-7901,hepatocarcinoma HEP-7402 and leukemia HL-60. Total-lignan has significant inhibition of cell proliferation and clone formation of human cancer cell lines such as SGC-7901 and BEL-7402,and its antitumor activities in vitro are higher than those of vincristine. Total-lignan from Stellera chamaejasme has a significant antitumor effect in vitro.