Clinical investigation of incomplete Kawasaki disease in Yi nationality of Liangshan
Dai Li
Abstract
Dai Li
Abstract
Objective To investigate the incidence,age structure,clinical features,complications and treatment conditions of incomplete Kawasaki disease in Liangshan Yi area in the past 9 years.Methods In this study,retrospective analysis and follow-up study were conducted on 83 confirmed cases of incomplete Kawasaki disease from hospitals in 17 counties of the prefecture,and the comparison was made with the complete Kawasaki disease.Results There were 83 confirmed cases of incomplete Kawasaki disease out of 307 cases of Kawasaki disease,with the proportion of incomplete Kawasaki disease.There were no significant differences in gender and age between incomplete Kawasaki disease and complete Kawasaki disease(P0.05).The most common clinical manifestation was fever,followed by the changes of oral mucosa,and lymphadenectasis was very rare.There were significant differences in the symptoms,except fever,between incomplete Kawasaki disease and complete Kawasaki disease(P0.05).Coronary artery lesions occurred in 37 cases,accounting for 44.58 percent of incomplete Kawasaki disease cases,indicating no significant difference from those of complete Kawasaki disease(P0.05).However,there was significant difference in incidence of moderate to severe coronary artery lesions between the complete and incomplete Kawasaki disease groups(P0.01).In the second week of the course of incomplete Kawasaki disease,platelets count significantly increased,while the white blood cells count decreased considerably,which were consistent with the symptoms of complete Kawasaki disease.Serum CRP concentration in incomplete Kawasaki disease group was 37.86±48.89mg/L,which was significantly lower than that in the complete Kawasaki disease group(P0.05).R-Globulin sensitivity of incomplete Kawasaki disease was high,which was significantly different from that of complete Kawasaki disease(P0.01).Conclusion The incidence rate of incomplete Kawasaki disease in Liangshan Yi area was higher than that in other large sample surveys in China.Age was not the main cause of incomplete Kawasaki disease.The differences in clinical features are not diagnostic indicators of incomplete Kawasaki disease.Cardiovascular damages,especially moderate to severe coronary artery lesions,continue to be the most common and serious complications of incomplete Kawasaki disease.
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Objective To investigate the incidence,age structure,clinical features,complications and treatment conditions of incomplete Kawasaki disease in Liangshan Yi area in the past 9 years.Methods In this study,retrospective analysis and follow-up study were conducted on 83 confirmed cases of incomplete Kawasaki disease from hospitals in 17 counties of the prefecture,and the comparison was made with the complete Kawasaki disease.Results There were 83 confirmed cases of incomplete Kawasaki disease out of 307 cases of Kawasaki disease,with the proportion of incomplete Kawasaki disease.There were no significant differences in gender and age between incomplete Kawasaki disease and complete Kawasaki disease(P0.05).The most common clinical manifestation was fever,followed by the changes of oral mucosa,and lymphadenectasis was very rare.There were significant differences in the symptoms,except fever,between incomplete Kawasaki disease and complete Kawasaki disease(P0.05).Coronary artery lesions occurred in 37 cases,accounting for 44.58 percent of incomplete Kawasaki disease cases,indicating no significant difference from those of complete Kawasaki disease(P0.05).However,there was significant difference in incidence of moderate to severe coronary artery lesions between the complete and incomplete Kawasaki disease groups(P0.01).In the second week of the course of incomplete Kawasaki disease,platelets count significantly increased,while the white blood cells count decreased considerably,which were consistent with the symptoms of complete Kawasaki disease.Serum CRP concentration in incomplete Kawasaki disease group was 37.86±48.89mg/L,which was significantly lower than that in the complete Kawasaki disease group(P0.05).R-Globulin sensitivity of incomplete Kawasaki disease was high,which was significantly different from that of complete Kawasaki disease(P0.01).Conclusion The incidence rate of incomplete Kawasaki disease in Liangshan Yi area was higher than that in other large sample surveys in China.Age was not the main cause of incomplete Kawasaki disease.The differences in clinical features are not diagnostic indicators of incomplete Kawasaki disease.Cardiovascular damages,especially moderate to severe coronary artery lesions,continue to be the most common and serious complications of incomplete Kawasaki disease.
Key concepts: Kawasaki disease, Medicine, Disease, Incidence (geometry), Artery, Pediatrics, Internal medicine, Gastroenterology