COMPARISON OF CLINICAL EFFECTS OF LASER EPITHELIAL KERATOMILEUSIS (LASEK) AND MULTI ZONE LASER IN SITU KERATOMILEUSIS (M-LASIK) FOR THE TREATMENT OF HIGH MYOPIA

Objective To contrast the clinical effects of Laser Epithelial Keratomileusis (LASEK) and multi zone Laser In Situ Keratomileusis (M-LASIK) for the treatment of high myopia. Methods 136 eyes of 75 high myo- pia patients were performed by LASEK and M-LASIK and were followed up for one year and more, the postoperative uncorrected visual acuity (UCVA) and the postoperative remain refraction and the Best Corrected Visual Acuity (BCUA) were analyzed. Results The average postoperative uncorrected visual acuity (UCVA)of M-LASIK group was better than that of LASEK group at early period (about 1 month later ) (p0.05), the average postoperative uncorrected visual acuity (UCVA) had no significant difference between two groups in 3 and 6 months (p0.05), the average postoperative uncorrected visual acuity (UCVA)of LASEK group were better than that of M-LASIK group in 1 year (p0.05). The postoperative uncorrected visual acuity (UCVA) were lower than the preoperative Best Corrected Visual Acuity (BCUA) both in two groups in 1 year (p0.05).The refractive status of two groups tend to regression, among these M-LASIK group was more obvious than LASEK group. The postoperative Best Corrected Visual Acuity (BCUA) had no significant difference between two groups in 1 year or more. Conclusion LASEK and M-LASIK can also effectively and safely treat high myopia with a thinner cornea, they have the same characteristics of saving cornea issues, more high myopic patients who have a thinner cornea can accepted laser surgery, but in long term follow up, regression may happen in two groups from mild hyperopia to mild myopia, uncorrected visual acuity (UCVA) and regressive rang of LASEK group were better than M-LASIK group.