2011•Journal of Northwest A&F UniversityRequires access
Effects of cinnamon on blood sugar and lipid levels in diabetic rats
Yongzhu Li
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Abstract
【Objective】 The study was conducted on the effects of cinnamon on blood sugar and lipid levels in diabetic rats.【Method】 The diabetic rats were induced by intraperitoneal injection of 200 mg/kg alloxan to establish diabetic model.The rats were divided into control group(Ⅰ),model group(Ⅱ),low dose cinnamon treating group(Ⅲ) and high dose cinnamon treating group(Ⅳ).The diabetic rats of group Ⅲ and Ⅳ were orally administered with 100 and 200 mg/(kg·d) cinnamon extract respectively,for 30 days.The rats of group Ⅰ and Ⅱ were orally administered with saline respectively by the same way and the same dose.The daily feed consume,water intake and urine excretion were recorded.The blood sugar,TC,TG,LDL-C,HDL-C level and the body weight were estimated at 0 and 30 d.【Result】 Compared with the rats of group Ⅰ,the body weight of all the diabetic rats of group(Ⅱ,Ⅲ and Ⅳ) decreased significantly(P0.05),and the blood sugar level increased significantly(P0.05) at 0 d.Compared with the rats of groupⅡ,the blood sugar,TC,TG,LDL-C level of the diabetic rats in group Ⅳdecreased significantly(P0.05),the body weight and HDL-C level increased significantly(P0.05) at 30 d.Compared with the rats of group Ⅰ,there were no differences in body weight,blood sugar,TC,TG,LDL-C and HDL-C level of the diabetic rats in group Ⅳ at 30 d(P0.05).【Conclusion】 The cinnamon extract(200 mg/(kg ·d)) decreased the blood sugar,TC,TG and LDL-C level of the diabetic rats induced by alloxan,increased the body weight and enhanced HDL-C level.Enrichment of cinnamon with cinnamate can provide a functional food spice that could potentially benefit human health.