Study on the chemical constituents in the flowers of Ligustrum lucium

OBJECTIVE To study the chemical constituents in the flowers of Ligustrum lucium Ait.METHODS Compounds were isolated and purified with silica gel and Pharmadex LH-20 column.Their structures were determined using spectroscopic analysis including MS and NMR.RESULTS 12 compounds were isolated and identified as follows: β-sitosterol(Ⅰ),daucosterol(Ⅱ),asergosta-7,22-dien-3β,5α,6β-triol(Ⅲ),naringenin(Ⅳ),luteolin(Ⅴ),apigenin(Ⅵ),quercetin(Ⅶ),apigenin-7-O-β-D-glucopyranoside(VIII),luteolin-7-O-β-D-glucopyranoside(Ⅸ),kaempferol-3-O-β-D-glucopyranoside(Ⅹ),quercetin-3-O-β-D-glucopyranoside(Ⅺ)and rutin(Ⅻ).CONCLUSION Compounds Ⅰ-Ⅵ,Ⅹ and Ⅺ were isolated from the flowers of Ligustrum lucium Ait.for the first time,and compounds Ⅲ,Ⅳ and Ⅴ were isolated from this plant for the first time.