Clinical analysis for the effect of omeprazole combined with famotidine in the treatment of reflux esophagitis

Objective To research and evaluate the efficacy of omeprazole combined with famotidine in the treatment of reflux esophagitis.Methods 120 cases of patients with reflux esophagitis in our hospital fromg Jan.2010 to Dec.2012 were retrospectively analyzed.They were randomly divided into 3 groups,40 cases of omeprazole group,40 cases of famotidine group,40 cases of omeprazole combined with famotidine group (joint group),the clinical efficacy of 3 groups were compared.Results The clinical treatment effect:the markedly efficacy rate of joint group was 72.5%,the total effctive rate was 97.5%;Omeprazole group was 42.5% and 72.5% respectively;Famotidine group was 20.0% and 57.5% respectively;the joint group was significantly higher than those of omeprazole group and famotidine group ( P0.05).The lesions under endoscope to improve the situation:markedly effective rate of the joint group was 70.0%,the total effective rate was 97.5%;Omeprazole group was 45.0% and 70.0% respectively;Famotidine group was 17.5% and 55.0% respectively;the joint group was significantly higher than those of omeprazole group and famotidine group ( P0.05).Conclusion The clinical effect of omeprazole combined with famotidine in the treatment of reflux esophagitis is good,and the security is better,it has become the main method for the treatment of reflux esophagitis,and promote the development of China′s treatment for reflux esophagitis in the future.