Cytogenetic analysis on Mongolian idiocy

Objective Cytogenetics method was analysed in Mongolian idiocy and the reason which induce the disease.Methods The method of cytogenetics as cell culture,plate,making,G banking and karyotype analysis ect,has been adopted in the cytogeneties study of patient's chromosome of pripheral blood lymphocyte.Result It was found that the karyotype of 21 patients were abnormal,including 18 ease of standard type,and2 case of translocation type,and 1 case of mosaic type.Conclusion:The cytogenetic technology is an use- ful method to diagnose chromosome abnormality-related disease Down syndrome is relation to mother~ age,genetics,enviroment,ect, factors and other.