The clinic analyses on fetus infection through uterus transmission of pregnant women with asymptomatic HBsAg positive

Objective: To study the risky factors of intrauterine transmission of hepatitis B virus (HBV). Methods: HBVmm and HBV DNA in the venous blood from HBsAg positive pregnant women and the umbilical blood from their newborns were studied. Results: The positive rate of HBV DNA of the pregnant women who were both positive for HBsAg and HBeAg and the positive rate of HBsAg of their newborns were significantly higher than that of other pregnant women. Conclusion: HBsAg, HBeAg positive mothers are the greatest threat to their fetus, if these women were injected with HBIG at the third trimesters, it may be good to hold up intrauterine transmission of hepatitis B virus.