ScholarLens Back to search
2007•Chinese Journal of PharmaceuticalsRequires access

Streptomycin-resistant Screening of High Yield Bleomycin A2 Producing Strain

Li Jian

Open publisher page 0 citations

Abstract

The method of streptomycin-resistance screening was applied to improve the productivity of bleomycin A2 by Streptomycin verticillus SIPI 7011. The UV light treated spores were smeared on agar plates containing 180μg/ml streptomycin. Among the one hundred and fifty-one streptomycin-resistant mutants, nineteen mutants had the higher bleomycin A2 yields than the original strain. The mutants with high bleomycin A2 productivity occurred at a high frequency(12.6%). The productivity of one mutant increased by 25% over the original strain.

About this research paper

What this paper is about

The method of streptomycin-resistance screening was applied to improve the productivity of bleomycin A2 by Streptomycin verticillus SIPI 7011. The UV light treated spores were smeared on agar plates containing 180μg/ml streptomycin. Among the one hundred and fifty-one streptomycin-resistant mutants, nineteen mutants had the higher bleomycin A2 yields than the original strain. The mutants with high bleomycin A2 productivity occurred at a high frequency(12.6%). The productivity of one mutant increased by 25% over the original strain.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

The method of streptomycin-resistance screening was applied to improve the productivity of bleomycin A2 by Streptomycin verticillus SIPI 7011. The UV light treated spores were smeared on agar plates containing 180μg/ml streptomycin. Among the one hundred and fifty-one streptomycin-resistant mutants, nineteen mutants had the higher bleomycin A2 yields than the original strain. The mutants with high bleomycin A2 productivity occurred at a high frequency(12.6%). The productivity of one mutant increased by 25% over the original strain.

Key concepts: Streptomycin, Strain (injury), Bleomycin, Mutant, Chemistry, Agar, Yield (engineering), Agar plate

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Streptomycin-resistant Screening of High Yield Bleomycin A2 Producing Strain — Research Paper | ScholarLens