Clinical observation for the usage of glucocorticoid in the treatment of SARS

Objective:To investigate the usage of glucocorticoid in the treatment of severe acute respiratory syndrome (SARS). Methods:Thirty cases of SARS patients' clinical data were analyzed retrospectively.Results: All thirty were given methyl prednisone or prednisone and other comprehensive treatments such as anti-infection and anti-virus.The dosages of methyl prednisone per day were 80mg to 360mg,and that of prednisone were 20mg to 30mg.SARS patients' symptoms were better controlled after two to four days treatments. But some patients' states deteriorated when the dosages of glucocorticoid were reduced too early. These patients states became stable by increasing glucocorticoid dosage and enhancing other comprehensive treatments. Conclusion: Reducing the usage of glucocorticoidinin the SAILS treatment too early may lead to the disease deteriorating.