Distribution of pathogenic bacteria and analysis of drug resistance in urinary tract infections

Objective To understand the changes of urinary tract infection pathogens in classification and drug resistance and to guide more rational use of antibiotics in clinic.Methods Pathogenic bacteria from patients diagnosed urinary tract infection and their susceptibility test results in vitro from 2001 to 2008 were collected and analyzed,ATCC25922,ATCC25923,ATCC27853 were selected as internal quality control strains.Results The positive rate of urine culture and ratios of various of pathogenic bacteria had no difference between from 2001 to 2004 and from 2005 to 2008.Escherichia coli,Enterococcus,Fungi,Enterobacter spp were the main grape isolated,Escherichia coli bacteria accounted for the most part,followed by enterococci.Gram-negative genus Bacillus had no difference in rates in various of pathogenic bacteria,but gram-positive cocci was significantly different between from 2001 to 2004 and from 2005 to 2008.From 2005 to 2008,the drug resistance rates in pathogen isolated from urine culture was significantly increased and quinolones was no longer the first choice for treatment of urinary tract infection.Conclusion With increasing in resistance to antibiotics of pathogens, clinicians should use antibiotics according to susceptibility test results.