2008•Journal of Xinjiang Agricultural UniversityRequires access

The Anti-senescence Effects of Lycium barbarum L. and Lycium barbarum L. and Pseudo-ginseng Compound

Shi Qing-hua

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Abstract

The anti-senescence effects of Lycium barbarum L.from Xinjiang and Lycium barbarum L.and pseudo-ginseng compound were studied.The experimental animal model of senescence was established with D-galactose injection.The xanthine oxidase method was introduced to detect the activity of the total superoxide dismutase(SOD) of the serum from mice in each group.While the thiobarbituric acid(TBA) method was used to find the quantity of malondialdehyde(MDA) of the serum from mice.Meanwhile the anti-fatigue experiment of animal was conducted and also observed the kidney's morphologic changes in mice.The results showed the effects of anti-oxidantion,anti-aging,anti-fatigue and other indicators in administration group were different from the senescence model group(P0.05 or 0.01).There were definite differences on glomerular morphology,basement membrane thickness,distribution window of endothelial cells between administration group and the senescence model group.The results showed the extraction of Lycium barbarum L.and Lycium barbarum L.and pseudo-ginseng compound have played a part role in anti-senescence,and the latter had a more significant effect.

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What this paper is about

The anti-senescence effects of Lycium barbarum L.from Xinjiang and Lycium barbarum L.and pseudo-ginseng compound were studied.The experimental animal model of senescence was established with D-galactose injection.The xanthine oxidase method was introduced to detect the activity of the total superoxide dismutase(SOD) of the serum from mice in each group.While the thiobarbituric acid(TBA) method was used to find the quantity of malondialdehyde(MDA) of the serum from mice.Meanwhile the anti-fatigue experiment of animal was conducted and also observed the kidney's morphologic changes in mice.The results showed the effects of anti-oxidantion,anti-aging,anti-fatigue and other indicators in administration group were different from the senescence model group(P0.05 or 0.01).There were definite differences on glomerular morphology,basement membrane thickness,distribution window of endothelial cells between administration group and the senescence model group.The results showed the extraction of Lycium barbarum L.and Lycium barbarum L.and pseudo-ginseng compound have played a part role in anti-senescence,and the latter had a more significant effect.

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Available abstract

The anti-senescence effects of Lycium barbarum L.from Xinjiang and Lycium barbarum L.and pseudo-ginseng compound were studied.The experimental animal model of senescence was established with D-galactose injection.The xanthine oxidase method was introduced to detect the activity of the total superoxide dismutase(SOD) of the serum from mice in each group.While the thiobarbituric acid(TBA) method was used to find the quantity of malondialdehyde(MDA) of the serum from mice.Meanwhile the anti-fatigue experiment of animal was conducted and also observed the kidney's morphologic changes in mice.The results showed the effects of anti-oxidantion,anti-aging,anti-fatigue and other indicators in administration group were different from the senescence model group(P0.05 or 0.01).There were definite differences on glomerular morphology,basement membrane thickness,distribution window of endothelial cells between administration group and the senescence model group.The results showed the extraction of Lycium barbarum L.and Lycium barbarum L.and pseudo-ginseng compound have played a part role in anti-senescence,and the latter had a more significant effect.

Key concepts: Lycium, Ginseng, Malondialdehyde, Senescence, Thiobarbituric acid, Chemistry, Superoxide dismutase, Fructose

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