Clinical analysis of chronic pulmonary disease cases complicated with fungal infections

Objective To analyze the clinical features of chronic pulmonary disease cases complicated with fungal infection. Methods The data of 542 chronic pulmonary disease cases complicated with fungal infection in respiratory department of internal medicine of our hospital were collected and analyzed. Results The most risk factors associated with chronic obstructive pulmonary disease complicated with fungal infections was long- term use of antibiotics,accounted for 46.1%. and followed by use of corticosteroids.(25.5%). Candida albicans was the The most common cause of pulmonary fungal infection accounted for 75.3%. The total effective rate of antifungal therapy was 80%. After anti- fungal treatment,458 cases cured and improved,accounted for 84.5%;no obvious efficacy was observed in 24 cases(4.4%),14 cases was deteriorated(2.6%) and 46 cases died accounted for 8.5% due underlying illness. Conclusions Attention should be paid to fungal infection in cases with chronic pulmonary disease in case of use of antibiotics and/or corticosteroids and effective intervention measures are indicated.