2001•Yanke xinjinzhanRequires access

Observation of electroretinography of the protective effects of flunarizine after ischemia and reperfusion injury in rabbit retina

You Li, Liu Y

Abstract

Objective To observe the protective effects of flunarizine on ischemia reperfusion injury in rabbit retina.Methods Retinal ischemia was induced in rabbits by increasing intraocular pressure to 16kPa for 60 minutes.The ERG b wave was examined before ischemia and 2,7,14 days after retinal ischemia reperfusion respectively.Flunarizine treated groups were given treatment for 12 hours before ischemia,and ischemia reperfusion 12 hours after reperfusion.Results The b wave amplitude of flunarizine treatment groups was restored to 80%.Conclusion Flunarizine was effective in protecting against ischemia reperfusion injury in rabbit retina.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Flunarizine, Ischemia, Medicine, Electroretinography, Erg, Retina, Reperfusion injury, Anesthesia