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2001•Journal of Jilin Military Medical College Fourth Military Medical UniversityRequires access

Effect of MMC on c-fos Expression of Cerebral Neurons in Mice

Yong Li

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Abstract

Objective To research the effect of MMC on c fos expression of cerebral neurons in mice.Methods In the test group 10 mg/kg MMC was injected into mouse abdominal cavity while in the control group normal saline of the same volume was administrated.Two hours later cerebral tissues were collected for effect observation of MMC on c fos expression by immuohistochemical method.Results MMC could induce c fos expression of cerebral neurons in mice.In the test group c fos positive rate of expression was significantly higher than that in the control group(P0.01).Conclusion MMC can induce c fos expression of cerebral neurons in mice.

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What this paper is about

Objective To research the effect of MMC on c fos expression of cerebral neurons in mice.Methods In the test group 10 mg/kg MMC was injected into mouse abdominal cavity while in the control group normal saline of the same volume was administrated.Two hours later cerebral tissues were collected for effect observation of MMC on c fos expression by immuohistochemical method.Results MMC could induce c fos expression of cerebral neurons in mice.In the test group c fos positive rate of expression was significantly higher than that in the control group(P0.01).Conclusion MMC can induce c fos expression of cerebral neurons in mice.

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Available abstract

Objective To research the effect of MMC on c fos expression of cerebral neurons in mice.Methods In the test group 10 mg/kg MMC was injected into mouse abdominal cavity while in the control group normal saline of the same volume was administrated.Two hours later cerebral tissues were collected for effect observation of MMC on c fos expression by immuohistochemical method.Results MMC could induce c fos expression of cerebral neurons in mice.In the test group c fos positive rate of expression was significantly higher than that in the control group(P0.01).Conclusion MMC can induce c fos expression of cerebral neurons in mice.

Key concepts: c-Fos, Saline, Gene expression, Chemistry, Ratón, Biology, Endocrinology, Internal medicine

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