Clinical study of mosapride in treating constipation type of irritable bowel syndrome overlapping with functional dyspepsia

Objective To explore the clinical efficacy of Mosapride on patients with constipation type of Irrita- ble Bowel Syndrome(IBS)overlapping with Functional Dyspepsia(FD). Methods 80patients with consti- pation type of IBS overlapping with FD were selected from the First People′s Hospital Of Shangqiu,from De- cember 2011to December 2012.They were randomly assigned into control group which received intestinal stress treatment or observer group which received Mosapride.4weeks after treatments,clinical effectiveness and clinical symptom score were collected and compared between two groups. Results After treatment,ef- fective rate in observer group was 90% which was statistically significant higher than 72.5%in control group(χ2=4.114 2,P0.05).Clinical symptom score in observer group was significantly lower than in control group(t=2.021 7,P0.05;t=1.992 8,P0.05;t=2.007 2,P0.05;t=2.050 5,P0.05).Clin- ical symptom score after treatment in observer group was significantly lower than before treatment(t=3.783 4, P0.01;t=2.859 2,P0.01;t=3.018 0,P0.01;t=3.292 4,P0.01). Conclusions Mosapride has a clear clinical effect on patients who have constipation type of IBS overlapping with FD.It′s very important to clinical treatment.