Clinical Research of Shuweifang on Reversing Pathological Changes of Gastric Mucosa in Patients with Chronic Atrophic Gastritis

Objective:To observe the effect of Shuweifang on reversing pathological changes of gastric mucosa in patients with chronic atrophic gastritis(CAG).Methods:One hundred and eighty-nine patients with CAG were randomly divided into 3 groups for parallel comparative study.Group I have 63 patients who were treated with Shuweifang and group II have 64 patients who were treated with Modified Shuweifang.Group three is the control group which has 62 patients treated with Weifuchun.Atrophy of glandular organ in gastric mucosa,intestinal metaplasia(IM),atypical hyperplasia(ATP),Helicobacter pyloric infection(Hp)and improvement of clinical symptoms were observed.Results:Pathological improvements were 73.02% for group I,73.44% for group II and 51.61% for control group(P0.05);relieve of symptoms were 6.16±2.73 for group I,5.08±4.86 for group II and 2.80±2.57 for control group(P0.01).There was no development of cancer in all the CAG cases during the treatment and follow-ups.Conclusions:Shuweifang has a significant effect on reversing CAG,IM and ATP in patients with CAG.It can relieve clinical symptoms and improve pathological changes of CAG.