Analysis of clinical manifestation in patients with acute tetramine poisoning

Objective To analyse the clinical significance of acute tetramine(TEM)poisoning.MethodTo observe the clinical symptom,physical sign and EEG changes of 67 patients with acute TEM poisoning,and to take dynamic observations about the hepatic function,activities of myocardial enzymes,ECG of patients between poisoning group and control group.ResultNausea and vomiting were the main symptoms and jerk was the main physical sign in acute TEM poisoning cases.The abnormality rate of EEG was 91.0%.The hepatic function and activities of myocardial enzymes in poisoning group were increased in some degree within the first day.On the third day the abnormality rates of ALT,TBIL,AST,CPK,LDH,α-HBDH,CK-MB,were 82.1%,56.7%,86.6%,98.5%,94.0%,89.6%,79.1% respectively. The myocardial enzymes levels of different stages were significant difference in comparative observation of the mild,moderate and serious poisoned patients (P0.001),the more serious,the higher activities of myocardial enzymes.The abnormality rate of ECG was 49.3%.Detection of myocardial enzymes had significant advantage over ECG examination.ConclusionAcute TEM poisoning can bring multi-organ damage.The damage to human body is reversible, and the sequelae are seldom observed.