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Interleukin2 as an adjuvent to increase the antibodies level of inactivated rabies virus vaccine

Pla Dalian

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Abstract

We were interested in determining whether the interleukin2 (IL2) could be an adjuvent to increase the immune response of mouse to inactivated rabies virus vaccine.BALB/c mice and Swiss mice were divided equally into two groups respectively.They were immunized by the inactivated rabies virus vaccine with IL2 or without IL2.The results showed that the antivirus IgGantibodies and virusneutralizing antibodies had appeared 5 days earlier for the group with IL2 than the one without IL2.The antibody titer had raised much higher for the group with IL2 than another one.

About this research paper

What this paper is about

We were interested in determining whether the interleukin2 (IL2) could be an adjuvent to increase the immune response of mouse to inactivated rabies virus vaccine.BALB/c mice and Swiss mice were divided equally into two groups respectively.They were immunized by the inactivated rabies virus vaccine with IL2 or without IL2.The results showed that the antivirus IgGantibodies and virusneutralizing antibodies had appeared 5 days earlier for the group with IL2 than the one without IL2.The antibody titer had raised much higher for the group with IL2 than another one.

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Available abstract

We were interested in determining whether the interleukin2 (IL2) could be an adjuvent to increase the immune response of mouse to inactivated rabies virus vaccine.BALB/c mice and Swiss mice were divided equally into two groups respectively.They were immunized by the inactivated rabies virus vaccine with IL2 or without IL2.The results showed that the antivirus IgGantibodies and virusneutralizing antibodies had appeared 5 days earlier for the group with IL2 than the one without IL2.The antibody titer had raised much higher for the group with IL2 than another one.

Key concepts: Rabies virus, Virology, Virus, Rabies, Antibody, Inactivated vaccine, Titer, Duck embryo vaccine

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