Diagnostic value of thinPrep cytologic test combined with colposcopy for cervical lesions

To evaluate the diagnostic value of thinPrep cytologic test(TCT)combined with colposcopy for cervical lesions. Biopsy under colposcopy was carried out for 150 women with positive TCT results(Study Group)and 135 women with suspicious cervical lesions(Control Group)in Chengdu No.6 People's Hospital from Oct 2009 to Oct 2011.Pathological diagnosis was used as the standard to compare the difference between the two groups. The sensitivity,specificity and diagnose accordance rates of TCT combined with colposcopy for cervical lesions were 94.12%,81.54%and 88.67%respectively,those for cervical intraepithelial neoplasia(CIN) were 81.25%,94.19%and 88.67%respectively,and those for squamous cell carcin oma(SCC) were 100%respectively.The sensitivity,specificity and diagnose accordance rates of colposcopy for inflammation and other benign lesions were 74.36%,47.37%and 62.96%respectively,those for CIN were 62.96%,73.75%and 73.75%respectively,and those for SCC were 73.75%,33.33%and 1.48%.Differences were significant between the two groups in the sensitivity,specificity and diagnose accordance rates(P 0.05). TCT combined with colposcopy is an important diagnostic method for cervical lesions.It can improve the detection rate of precancerous cervical lesions.