2010•Chinese Journal of PharmaceuticalsRequires access
Quality Standard for Alkaloid Extract of Peganum harmala L.
Changhong Wang, Satcm Key
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Abstract
The quality control of alkaloid extract from Peganum harmala L.was carried out through TLC and HPLC methods with harmaline and harmine as index ingredients.The experimental samples and reference substances in TLC showed the identical spots with same color and shape at the same position.The results including moisture,ash,water extracts and heavy metals were in consistent with the regulations of Chinese Pharmacopoeia.An HPLC method was used for the determination of harmaline and harmine in the extract.The calibration curves of harmaline and harmine were linear in the concentration ranges of 2 200 and 0.8 320 μg/ml,respectively.Their recoveries were 99.7% and 100.7%,with RSDs of 1.89% and 1.78%.The intraand inter-day RSDs were less than 2%.