2011•China Medical HeraldRequires access
The clinical application of soluble transferrin receptor in chronic anemia
Shuying Zhang
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Abstract
Objective:To discuss the clinical application of soluble transferrin receptor in chronic anemia.Methods:63 cases of patients with chronic anemia were divided into chronic anemia with iron deficiency group(30 cases) and chronic anemia without iron deficiency group(33 cases),23 cases of healthy person were divided into healty group.The concentration of sTFR was detected by the method of biotin-affinity grain enzyme-linked immunosorbent,and the results were comparison analyzed combination the level of TIBC,SI,SF.Results:The sTFR level of chronic anemia with iron deficiency group was(46.1±29.4) nmol/L;the sTFR level of chronic anemia without iron deficiency group was(18.4±5.7) nmol/L;the sTFR level of healty group was(15.5±6.2) nmol/L;the sTFR level of chronic anemia with iron deficiency group were significantly higher than that of other groups(P0.01);there was no significant difference between chronic anemia without iron deficiency group and healty group(P0.05).Conclusion:sTFR is an sensitive and reliable quantitative index to diagnose iron deficiency.It has great clinical value in evaluation iron's situation of chronic anemia population.