2006•Journal of Practical Diagnosis and TherapyRequires access
Clinical study on paclitaxel plus cisplatin in the treatment of advanced non-small cell lung cancer
Lida Shen
Open publisher page 0 citations
Abstract
Objective To evaluate the results of paclitaxel plus cisplatin in the treatment of advanced non-small cell lung cancer.Methods Thirty patients with advanced non-small cell lung cancer received paclitaxel 85 mg/m~2 by intravenous infusion on day 1,8,15 and cisplatin 20 mg/m~2 by intravenous infusion on day 1 to 5.The treatment was repeated every 28 days,up to 3 courses.Results Of all cases, 1 got complete response(3.3%),15 got partial response(50%),with an overall rate of(53.3%).The main toxicities were myelosuppression,nausea and vomiting, and other side effects were mild.Conclusion A high response rate can be obtained in advanced non-small cell lung cancer by paclitaxel plus cisplatin.Paclitaxel is a promising antitumor agent with tolerable toxicity