2005•Journal of Clinical CardiologyRequires access

The short-term prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes

Sun Tongwen

Abstract

Objective: To investigate the short-term prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes(ACS). Method:A total of 106 patients with acute coronary syndrome,whose blood BNP concentrations were measured with Triage BNP test,within 13 days after onset of ischemia symptoms,were divided into 2 groups:the survival and the non-survival, according to the results of 1 mouth follow - up. Result:The blood BNP concentration in the non-survival was significantly higher than in the survival;univariate analysis showed that ,BNP (172 ng/L,median)and Killip class (Ⅱ Ⅳ) were prognostic factors of short-term cardiac death in patients with ACS(P 0.01);Logistic regression analysis indicated that smoking and BNP(596 ng/L,75% percentile) were independent predictors of short-term cardiac death in patients with ACS (OR= 5.5, P 0.05;OR= 21.19, P 0.01).Conclusion:Blood BNP level was related to short-term prognosis in patients with ACS.

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Key concepts: Medicine, Internal medicine, Natriuretic peptide, Acute coronary syndrome, Cardiology, Univariate analysis, Killip class, Logistic regression