Inhibiting effects of four Chinese medicinal herb on enterococcus faecalis in the infected root canals

Objective The purpose of this study was to compare the inhibiting effects of four Chinese medicinal herb decoctions(such as Coptis chinensis Franch) on Enterococcus Faecals in the infected root canals.Methods A total of 84 single-rooted extracted human teeth were used in this study.The teeth were randomly divided into four groups(Coptis chinensis Franch decoction group,Schisandra Chinensis decoction group,Chinese rhubarb decoction group and Frucrus forsythia decoction group) and three control groups(FC group,negative control group,and positive control group).Every group contained 12 teeth.The E.faecalis infected root canal models were manufactured after normal root canal preparation and sterilization.The teeth of negative control group was not infected by bacteria,and placed in 0.9% sodium chloride injection.The other teeth were infected by E.faecalis and treated with different Chinese medical herbs decoction separately.Transmittances of each group were measured after 3 days and 7 days.Results There was no difference in the following comparisons,Coptis chinensis Franch decoction group(3 d) and FC group(3 d) comparison,Frucrus Forsythia decoction group(3 d) and positive control group(3 d) comparison,Frucrus Forsythia decoction group(3 d) and negative control group(7d) comparison,Chinese rhubarb decoction group(3 d),Coptis chinensis Franch decoction group(7 d) and FC group(7 d) comparison,Frucrus Forsythia(7 d) and positive control group(7 d) comparison,(P0.05).There were statistical significance in the other groups.(P0.05).Conclusions In the four Chinese medical herbs mentioned above,Coptis chinensis Franch,Schisandra Chinensis and Chinese rhubarb had inhibition effects on E.faecalis at different levels.Among the four Chinese medical herbs,the most powerful one was Coptis chinensis Franch,that has the same inhibition effects as FC.Frucrus Forsythia has no inhibition effects on E.faecalis.