Analysis of variation of BMD in 105 patients with type 2 diabetes mellitus

Objective To further understand an effect of diabetes on metabolism of bone, we investigated the rule of variation of BMD and clinical features of the patients with Ⅱ type diabetes Methods By detecting the value of BMD in lumbar vertebyae (L 1 L 4),neck of femur, greater trochanter of femur in 105 cases of patients with Ⅱ type diabetes using Dual energy X ray absorptiometry (DEXA) We also detected the value of BMD in healthy with the same age and the same sex as control group Results 1, There is no obvious difference of the detected value of BMD between the female patients with Ⅱ type diabetes and the control group with the same age 2, There is obvious difference of the detected value of BMD in male patients with Ⅱ type diabetes at 51 60 year group And there is no obvious difference in the group that is beyond 61 years 3, The detected value of BMD in male patients with Ⅱ type diabetes is obvious higher than that in female patients at the same age The detected value of BMD in the Ward's triangular zone is obvious lower than that in lumbar vertebrae, neck of femur, greater trochanter at every age group Conclusions 1, The decrease of oestrogenic hormone level is the main reason of osteoporosis in the postmenopausal women 2, The Ⅱ type diabetes could cause osteoporosis in some aged patients 3,The variation of value of BMD in osteoporosis at first appears in the Ward's triangular zone