The Mechanism Study of Hemorheology in Hypertensive Rats with Cerebral Infarction Induced by Sudden Rising of Temperature

Objective:To study the mechanism of hemorheology in hypertensive rats with cerebral infarction induced by sudden rising of temperature.Methods:Rats models of strokes prone to renovascular hypertensive(RHRSP) were established by the improved Huang Ruxun and were put in man-made sudden rising of temperature to induce cerebral infarction.Detect the changes of the blood viscosity, erythrocyte aggregation and electrophoresis before and after temperature rising.Results:The blood viscosity, erythrocyte aggregation and electrophoresis of all rats were heightened by sudden rising of temperature, having the largest range ability in the model group;when the temperature stopped rising, the blood viscosity of rats in normal group and sham-operated group descended, but the model group was still ascending(P0.05 or P0.01).Moreover, the three indexes of model group of cerebral infarction rats were higher than those of normal and sham-operated rats at the same time after rising temperature(P0.05 or P0.01).Conclusions:Sudden rising of temperature leads hemorheology to fluctuate, resulting in a poor recovery capability.The large range ability and long persistence time of the blood viscosity to change was an important mechanism of hypertensive organism with induced cerebral infarction.