2011Zhongguo yiyuan ganranxue zazhiRequires access

Nosocomial infection caused by acinetobacter baumannii isolated from ICU and its drug resistance

HE Gui-yuan

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Abstract

OBJECTIVE To provide the evidences for preventing the infections caused by bacteria,and to monitor the distribution and resistance of Acinetobacter baumannii in ICU.METHODS The distribution and drug susceptibility of 96 strains of A.baumannii in nosocomial infections from 2007 to 2009 were retrospectively analyzed.RESULTS A.baumannii infections in hospital had increased in recent years.A.baumannii was mainly isolated from respiratory tract secretion samples(82.3%).The isolation rate of A.baumannii tended to rise.Its cross resistance to antibiotics was rather high.The resistant rate of A.baumannii to cefoperazone/sulbactam(2.1%) was the lowest,then to meropenem(14.6%) and imipenem(17.7%).CONCLUSION The antimicrobial resistance of A.baumannii is serious in ICU.It is urgent to carry out the surveillance to bacterial resistance for the rational use of antibiotics in order to decrease the morbidity and fatality rates.

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OBJECTIVE To provide the evidences for preventing the infections caused by bacteria,and to monitor the distribution and resistance of Acinetobacter baumannii in ICU.METHODS The distribution and drug susceptibility of 96 strains of A.baumannii in nosocomial infections from 2007 to 2009 were retrospectively analyzed.RESULTS A.baumannii infections in hospital had increased in recent years.A.baumannii was mainly isolated from respiratory tract secretion samples(82.3%).The isolation rate of A.baumannii tended to rise.Its cross resistance to antibiotics was rather high.The resistant rate of A.baumannii to cefoperazone/sulbactam(2.1%) was the lowest,then to meropenem(14.6%) and imipenem(17.7%).CONCLUSION The antimicrobial resistance of A.baumannii is serious in ICU.It is urgent to carry out the surveillance to bacterial resistance for the rational use of antibiotics in order to decrease the morbidity and fatality rates.

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Available abstract

OBJECTIVE To provide the evidences for preventing the infections caused by bacteria,and to monitor the distribution and resistance of Acinetobacter baumannii in ICU.METHODS The distribution and drug susceptibility of 96 strains of A.baumannii in nosocomial infections from 2007 to 2009 were retrospectively analyzed.RESULTS A.baumannii infections in hospital had increased in recent years.A.baumannii was mainly isolated from respiratory tract secretion samples(82.3%).The isolation rate of A.baumannii tended to rise.Its cross resistance to antibiotics was rather high.The resistant rate of A.baumannii to cefoperazone/sulbactam(2.1%) was the lowest,then to meropenem(14.6%) and imipenem(17.7%).CONCLUSION The antimicrobial resistance of A.baumannii is serious in ICU.It is urgent to carry out the surveillance to bacterial resistance for the rational use of antibiotics in order to decrease the morbidity and fatality rates.

Key concepts: Acinetobacter baumannii, Cefoperazone, Meropenem, Imipenem, Drug resistance, Medicine, Sulbactam, Antibiotics

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