2007•Chinese Journal of Laboratory DiagnosisRequires access

Study of serum anti with Rh hemolytic disease of the newborn

Suiyong Zhu

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Abstract

Objective To study of serum anti 20 patients with Rh hemolytic disease of the newborn.Methods ABO extracardiac antibody is detected with deploying straight Coombs'test,liberation antibody,irradiation test,antibodies accredit with tester microcolumn gel coombs test.Results Of the 20 patients with Rh hemolytic disease,11 patients were provoked by anti-D and 4 patients were by anti-D and other Rh system antibody,occupying 75%.3 patients were provoked by anti-E and 1 patient were provoked by anti-E and anti-c,occupying 20%.1 patient were provoked by anti-C,occupying 5%.And 20 patients mothers had already haved childbearing or miscarriage or blood transfusion.Conclusion To prevent beforehand Rh hemolytic disease of the newborn,It is essential that Rh blood group of the couple are detected and gravida Rh system antibody are screened before gravida childbearing especially before gravida childbearing who had already haved childbearing or miscarriage or blood transfusion.

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Objective To study of serum anti 20 patients with Rh hemolytic disease of the newborn.Methods ABO extracardiac antibody is detected with deploying straight Coombs'test,liberation antibody,irradiation test,antibodies accredit with tester microcolumn gel coombs test.Results Of the 20 patients with Rh hemolytic disease,11 patients were provoked by anti-D and 4 patients were by anti-D and other Rh system antibody,occupying 75%.3 patients were provoked by anti-E and 1 patient were provoked by anti-E and anti-c,occupying 20%.1 patient were provoked by anti-C,occupying 5%.And 20 patients mothers had already haved childbearing or miscarriage or blood transfusion.Conclusion To prevent beforehand Rh hemolytic disease of the newborn,It is essential that Rh blood group of the couple are detected and gravida Rh system antibody are screened before gravida childbearing especially before gravida childbearing who had already haved childbearing or miscarriage or blood transfusion.

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Available abstract

Objective To study of serum anti 20 patients with Rh hemolytic disease of the newborn.Methods ABO extracardiac antibody is detected with deploying straight Coombs'test,liberation antibody,irradiation test,antibodies accredit with tester microcolumn gel coombs test.Results Of the 20 patients with Rh hemolytic disease,11 patients were provoked by anti-D and 4 patients were by anti-D and other Rh system antibody,occupying 75%.3 patients were provoked by anti-E and 1 patient were provoked by anti-E and anti-c,occupying 20%.1 patient were provoked by anti-C,occupying 5%.And 20 patients mothers had already haved childbearing or miscarriage or blood transfusion.Conclusion To prevent beforehand Rh hemolytic disease of the newborn,It is essential that Rh blood group of the couple are detected and gravida Rh system antibody are screened before gravida childbearing especially before gravida childbearing who had already haved childbearing or miscarriage or blood transfusion.

Key concepts: Medicine, Rh blood group system, Hemolytic disease of the newborn (ABO), Antibody, Coombs test, ABO blood group system, Haemolytic disease, Miscarriage

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