Painful ophthalmoplegia caused by aspergillosis

Objective:To investigate the clinic characters and diagnosis of aspergillosis leading to painful ophthalmoplegia(APOP).Methods:One patient was systematically studied and literatures were reviewed by the authors.Results:Aspergillosis was one of the reasons resulting in painful ophthalmoplegia.The onset was urgent and process progress was quick in APOP,It could involve cavernous sinus,accessory nasal cavity,orbital apex and internal carotid artery,showing ophthalmoplegia,retro-orbit pain,peri-orbit pain,vision disorder,hemiparalysis,et al.Biopsy could provide cue to aspergillosis.Conclusion:APOP can be misidentified,but can be diagnosed with history,physical examination,CT,MRI and Biopsy.