The application of controlled hypotension with remifentanil in nasal endoscopic surgery

Objective To study the efficacy and safety of sodium nitroprusside(SNP) with remifentanil used for controlled hypotension in nasal endoscopic surgery.Methods Sixty children undergoing operation were randomly divided into A and B group.Local anesthesia was in A group;Anesthesia was maintained with the continuous infusion of remifentanil and propofol in B group.Controlled hypotension was performed and the MAP was reduced and maintained between 60~70 mmHg with the continuous infusion of SNP.Hemodynamic changes before operation,in operation and 10 min after operation were observed.Results Data in B groups showed high satisfaction with hypotension,HR was stability in B group.Hemodynamic changes were better in B group than in A group(P0.05).Conclusions Remifentanil could potentiate the hypotensive effect of SNP,decrease the bleeding amount,shorten the operation time and maintain a stable hemodynamics during controlled hypotension.