Analysis on the relationship of type 2 diabetes patients with acute glucose fluctuations and carotid artery intima-media thickness of cerebral infarction

Objective To investigate the relationship of T2 DM with acute glucose fluctuations and IMT. Methods Forty-five cases of T2 DM patients were selected from January 2013 to 2014 February in our hospital as T2 DM group,50 cases of T2 DM patients with acute cerebral infarction were selected in our hospital on the same period with T2 DM group as DMCI group,the carotid artery IMT of two groups were measured, the patients in the DMCI group were divided into IMT thickening group(n=29), IMT normal group(n=21), the data of every groups were compared and the correlation of IMT with other indicators were analyzed. Results 1 SBP, DBP, LDL-C, TC, TG, HbA1 C, IMT, MAGE of DMCI group were higher than T2 DM group, the difference was significant(P 0.05). 2SBP, LDL-C, IMT, MAGE IMT of IMT thickening group was significantly higher than IMT normal group, the difference was significant(P 0.05). 3MAGE,LDL-C, SBP were the influence factors for IMT(P 0.05). Conclusion Patients with high blood sugar stable and efficient glucose lowering blood sugar fluctuations can reduce the risk of atherosclerosis, reduce the incidence of diabetic complications.