Distribution of pathogens in bile of pathents with biliary tract infection and analysis on its drug resistance

Objective To study the distribution,drug resistance and antibiotics sensitivity of pathogenic bacteria in bile of patients with biliary tract infection,and provide clinical reference for antibiotic selection.Methods Patients from January 2004to December 2012 in the Third People's Hospital of Xiaoshan District in Zhejiang Province were selected as study objects,the bile samples with biliary tract infection were tested,and its pathogens were separated,cultured,and identified,the pathogen drug sensitivity were tested by K-B Paper plate method.Results fungus in bile of patients with biliary tract infection was 77(18.08%),gram-positive bacteria was 57(13.38%),gram-negative bacteria was 292(68.54%),and the gram-negative bacteria was the main pathogens including pseudomonas aeruginosa was 64(21.91%),escherichia coli was 96(32.88%),candida albicans was 58(19.86%),klebsiella pneumoniae job strain was 45(15.41%),feces enterococcus was 29(9.93%) and so on.susceptibility results showed that gram-negative bacteria resistant to meropenem lowest rate.Conclusion Most patients with biliary tract infection are gram-negative bacilli infections,the fungi has a higher detection rate,most of them are multi-drug resistant strains,and there is an upward trend,so appropriate selection of antibiotics in the clinical should be based on the results of medicine sensitive experiment.