Beneficial effects of abdominal aorta block on the heamodynamic stability of the dog undergoing orthotopic liver transplantation with veno-venous bypass

Objective To investigate the heamodynamic changes during orthotopic liver transplantation with veno-venous bypass in the dog, and to evaluate the beneficial effects of abdominal aorta block in the anhepatic phase.Methods Of the 12 canine liver transplants performed under general anesthesia in this study, there were two groups: the control group(group I), i.e. orthotopic liver transplantation with veno-venous bypass; and the experimental group(group II),where the abdominal aorta was blocked in the anhepatic phase during orthotopic liver transplantation with veno-venous bypass. The date of heart rate and mean arterial blood pressure were measured at following occasion: after intubation, dissection phase, anhepatic phase, reperfusion phase and the end of operation.Results There was no significant difference in the hemodynamic changes between the two groups before anhepatic phase (P0.05),but in the anhepatic phase and reperfusion phase, the hemodynamic data were more stable in group II than group I (P0.05).Conclusion The use of abdominal aorta block in the anhepatic phase can be a valuable alternative treatment for heamodynamic stability during orthotopic liver transplantation with veno-venous bypass. Accordingly it will meliorate the successful rate of the operation.