2012•Hainan Yixueyuan xuebaoRequires access

The efficacy of budesonide and terbutaline inhalation on child asthma

Bing Wang

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Abstract

Objective: To investigate the efficacy of budesonide and terbutaline inhalation for child asthma.Methods: A total of 64 pediatric cases of asthma were randomly divided into study group and control group with 32 cases in each group.Budesonide(1 ~ 2 mL,including budesonide 0.5 ~ 1 mg),and terbutaline(1 ~ 2 mL,including terbutaline 0.25 ~ 0.5mg) were added to normal saline(2 ~ 3 mL) and was given to the treatment group for inhalation after atomization,10 ~ 15 min per time and 2 ~ 3 times per day.The control group was given aminophylline(4~5mg/kg) and hydrocortisone(5 ~ 10mg/kg) for intravenous drip,once per day for 5 ~ 7d.Clinical efficacy and symptoms of the two groups were observed and compared.Results: The treatment group showed significant shorter recovery time than the control group regarding to symptoms of coughing,wheezing,crackles(P0.05);It also showed better clinical efficacy than the control group(P0.05).No obvious adverse reactions were observed in both groups(P 0.05).There's no significant difference in changes of breathing frequency between the two groups(P0.05) but significant difference in the increase of heart rate were observed(P0.05).Conclusions:Budesonide combing with terbutaline for inhalation after atomization is effective on child asthma with advantages of easy manipulation and low incidence of side effects.

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What this paper is about

Objective: To investigate the efficacy of budesonide and terbutaline inhalation for child asthma.Methods: A total of 64 pediatric cases of asthma were randomly divided into study group and control group with 32 cases in each group.Budesonide(1 ~ 2 mL,including budesonide 0.5 ~ 1 mg),and terbutaline(1 ~ 2 mL,including terbutaline 0.25 ~ 0.5mg) were added to normal saline(2 ~ 3 mL) and was given to the treatment group for inhalation after atomization,10 ~ 15 min per time and 2 ~ 3 times per day.The control group was given aminophylline(4~5mg/kg) and hydrocortisone(5 ~ 10mg/kg) for intravenous drip,once per day for 5 ~ 7d.Clinical efficacy and symptoms of the two groups were observed and compared.Results: The treatment group showed significant shorter recovery time than the control group regarding to symptoms of coughing,wheezing,crackles(P0.05);It also showed better clinical efficacy than the control group(P0.05).No obvious adverse reactions were observed in both groups(P 0.05).There's no significant difference in changes of breathing frequency between the two groups(P0.05) but significant difference in the increase of heart rate were observed(P0.05).Conclusions:Budesonide combing with terbutaline for inhalation after atomization is effective on child asthma with advantages of easy manipulation and low incidence of side effects.

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Available abstract

Objective: To investigate the efficacy of budesonide and terbutaline inhalation for child asthma.Methods: A total of 64 pediatric cases of asthma were randomly divided into study group and control group with 32 cases in each group.Budesonide(1 ~ 2 mL,including budesonide 0.5 ~ 1 mg),and terbutaline(1 ~ 2 mL,including terbutaline 0.25 ~ 0.5mg) were added to normal saline(2 ~ 3 mL) and was given to the treatment group for inhalation after atomization,10 ~ 15 min per time and 2 ~ 3 times per day.The control group was given aminophylline(4~5mg/kg) and hydrocortisone(5 ~ 10mg/kg) for intravenous drip,once per day for 5 ~ 7d.Clinical efficacy and symptoms of the two groups were observed and compared.Results: The treatment group showed significant shorter recovery time than the control group regarding to symptoms of coughing,wheezing,crackles(P0.05);It also showed better clinical efficacy than the control group(P0.05).No obvious adverse reactions were observed in both groups(P 0.05).There's no significant difference in changes of breathing frequency between the two groups(P0.05) but significant difference in the increase of heart rate were observed(P0.05).Conclusions:Budesonide combing with terbutaline for inhalation after atomization is effective on child asthma with advantages of easy manipulation and low incidence of side effects.

Key concepts: Budesonide, Medicine, Terbutaline, Inhalation, Aminophylline, Asthma, Anesthesia, Saline

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