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Research Progress of Calpain System Gene

Mohan Qiu

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Abstract

Clpain system consists of calpainⅠ(CAPN1),calpainⅡ(CAPN2),calpastatin(CAST) and muscle specific calpain,CAPN3.Calpain system is probably the major proteolytic enzyme in protein degradation,which plays an important role in myofibrillar protein degradation.The muscle growth and postmortem tenderization of meat are highly related to the degree of proteolysis,so the activity of calpain system has an effect on muscle growth and meat tenderness.The article reviewed the structure,activity regulation,function mechanism,effects on meat quality and discussed the application prospect of calpain system.

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What this paper is about

Clpain system consists of calpainⅠ(CAPN1),calpainⅡ(CAPN2),calpastatin(CAST) and muscle specific calpain,CAPN3.Calpain system is probably the major proteolytic enzyme in protein degradation,which plays an important role in myofibrillar protein degradation.The muscle growth and postmortem tenderization of meat are highly related to the degree of proteolysis,so the activity of calpain system has an effect on muscle growth and meat tenderness.The article reviewed the structure,activity regulation,function mechanism,effects on meat quality and discussed the application prospect of calpain system.

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Available abstract

Clpain system consists of calpainⅠ(CAPN1),calpainⅡ(CAPN2),calpastatin(CAST) and muscle specific calpain,CAPN3.Calpain system is probably the major proteolytic enzyme in protein degradation,which plays an important role in myofibrillar protein degradation.The muscle growth and postmortem tenderization of meat are highly related to the degree of proteolysis,so the activity of calpain system has an effect on muscle growth and meat tenderness.The article reviewed the structure,activity regulation,function mechanism,effects on meat quality and discussed the application prospect of calpain system.

Key concepts: Calpain, Calpastatin, Proteolysis, Myofibril, Tenderness, Meat tenderness, Cell biology, Gene

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